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. 2015;56(4):1269-77.

The prognostic role of EBER in pediatric cancer

Simona Sorana Căinap  1 , Bogdan Fetică, Rareş Buiga, Călin Căinap, Anne-Marie Constantin, Alina Simona Şovrea
Affiliations
  • PMID: 26743271
Free article

The prognostic role of EBER in pediatric cancer

Simona Sorana Căinap et al. Rom J Morphol Embryol. 2015.
Free article

Abstract

The Epstein-Barr virus (EBV) infection is an endemic disease, over 90% of the population being exposed to it by adulthood. EBV is implicated in the etiology of a significant number of neoplasms, which acquire particular features in terms of course and prognosis. Incidence rates are much higher in children. To establish the link between EBV and neoplasms, EBER (Epstein-Barr virus non-encoded RNAs) needs to be highlighted in tumor tissue. The role of EBV in patient response to oncological treatment remains controversial.

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