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. 2016 Feb 1;213 Suppl 1(Suppl 1):S15-8.
doi: 10.1093/infdis/jiv411.

Age-Specific Incidence Rates for Norovirus in the Community and Presenting to Primary Healthcare Facilities in the United Kingdom

Sarah J O'Brien  1 , Anna L Donaldson  2 , Miren Iturriza-Gomara  3 , Clarence C Tam  4
Affiliations

Age-Specific Incidence Rates for Norovirus in the Community and Presenting to Primary Healthcare Facilities in the United Kingdom

Sarah J O'Brien et al. J Infect Dis. .

Abstract

In a prospective, population-based cohort study and a study of primary-healthcare consultations, we had a rare opportunity to estimate age-specific rates of norovirus-associated infectious intestinal disease in the United Kingdom. Rates in children aged <5 years were significantly higher than those for other age groups in the community (142.6 cases per 1000 person-years [95% confidence interval {CI}, 99.8-203.9] vs 37.6 [95% CI, 31.5-44.7]) and those for individuals presenting to primary healthcare (14.4 cases per 1000 person-years [95% CI, 8.5-24.5] vs 1.4 [95% CI, .9-2.0]). Robust incidence estimates are crucial for vaccination policy makers. This study emphasises the impact of norovirus-associated infectious intestinal disease, especially in children aged <5 years.

Keywords: acute gastroenteritis; community; incidence; norovirus; pediatric; policy; prevention; primary healthcare; real-time/quantitative RT-PCR; vaccination.

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References

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