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. 2016:19:109-11.
doi: 10.1016/j.ijscr.2015.12.042. Epub 2015 Dec 28.

Giant leiomyosarcoma: A case report

Taylan Senol  1 , Ilker Kahramanoglu  2 , Bahar Muezzinoglu  3 , Izzet Yucesoy  1
Affiliations

Giant leiomyosarcoma: A case report

Taylan Senol et al. Int J Surg Case Rep. 2016.

Abstract

Introduction: Uterine leiomyosarcoma is a rare uterine malignancy. Most of the patients lack symptoms or present with a rapidly enlarging pelvic mass.

Presentation of case: We report on a very large leiomyosarcoma in a woman presenting with a 3 months history of rapidly growing adominal mass and fatigue. Laparotomy was performed and diagnosis was confirmed by pathologic and histologic analysis. Patient refused chemotherapy after surgery and died from recurrence at 4th postoperative month.

Discussion: Uterine leiomyosarcomas may follow a rapid clinical course with a doubling time of four weeks. There is no reliable method to distinguish uterine sarcoma from benign leiomyomas preoperatively.

Conclusion: This case represents the largest leiomyosarcoma reported in the literature.

Keywords: Leiomyoma; Leiomyosarcoma; Size.

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Figures

Fig. 1
Fig. 1
Preoperative view of the patient in supine position.
Fig. 2
Fig. 2
Intraoperative view of the uterus.
Fig. 3
Fig. 3
Gross appearance of the tumor.
Fig. 4
Fig. 4
Majority of the tumor cell nuclei stained with Ki67 proliferation marker (immunohistochemistry) × 100.
See this image and copyright information in PMC

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