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Review
. 1989 Oct 12;321(15):1014-22.
doi: 10.1056/NEJM198910123211505.

Liver transplantation (1)

Affiliations
Review

Liver transplantation (1)

T E Starzl et al. N Engl J Med. .

Abstract

Advances in the management of both chronic and acute hepatic disease have been made possible and even mandated by the development of liver transplantation. The clinical use of transplantation has proceeded at a rapid pace since a Consensus Development Conference of the National Institutes of Health concluded in June 1983 that liver transplantation had become a service and not simply an experimental procedure.

The liver can be transplanted as an extra (auxiliary) organ at an ectopic site, or in the orthotopic location after the removal of the host liver (Fig. 1). This article will focus primarily on the orthotopic procedure. However, there has been renewed interest in the auxiliary operation, which will be discussed separately.

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Figures

Figure 1
Figure 1. Orthotopic Liver Transplantation
Biliary reconstruction can be accomplished through choledochojejunostomy or duct-to-duct anastomosis (inset).

References

    1. National Institutes of Health Consensus Development Conference Statement: liver transplantation — June 20–23, 1983. Hepatology. 1983 Suppl:107S–110S. - PubMed
    1. Starzl TE, Iwatsuki S, Van Thiel DH, et al. Evolution of liver transplantation. Hepatology. 1982;2:614–36. - PMC - PubMed
    1. Darby JM, Stein K, Grenvik A, Stuart SA. Approach to management of the heart beating ‘brain dead’ organ donor. JAMA. 1989;261:2222–8. - PubMed
    1. Popper H. Coming of age. Hepatology. 1985;5:1224–6. - PubMed
    1. Makowka L, Gordon RD, Todo S, et al. Analysis of donor criteria for the prediction of outcome in clinical liver transplantation. Transplant Proc. 1987;19:2378–82. - PMC - PubMed

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