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Comment
. 2016 Jan 19;113(3):473-5.
doi: 10.1073/pnas.1522938113. Epub 2016 Jan 8.

Driven to metastasize: Kinases as potential therapeutic targets in prostate cancer

Felix Y Feng  1 , Vishal Kothari  2
Affiliations
Comment

Driven to metastasize: Kinases as potential therapeutic targets in prostate cancer

Felix Y Feng et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

Conflict of interest statement: F.Y.F. has previously served on advisory boards for Celgene and Medivation/Astellas, and has received a research grant from Celgene for investigation of the use of DNA-dependent protein kinase (DNAPK) inhibitors in prostate cancer.

Figures

Fig. 1.
Fig. 1.
Kinase inhibitors as a therapeutic strategy for mCRPC. Using preclinical models of prostate cancer, kinases that potentially drive metastatic progression may be identified through in vivo screening assays for metastases, as described by Faltermeier et al. (4). Upon identification of biomarkers of response, patients could be selected for treatment with a specific kinase inhibitor to optimize the potential for disease response.
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References

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