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. 2016 Jan 7;18(1):7-9.
doi: 10.1016/j.stem.2015.12.008.

Lifting the Mist on Gastric Stem Cells

Julia Varga  1 , Florian R Greten  2
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Lifting the Mist on Gastric Stem Cells

Julia Varga et al. Cell Stem Cell. .
Free article

Abstract

In a recent issue of Cancer Cell, Hayakawa et al. (2015) demonstrate that Mist1(+) gastric stem cells are supported by a specialized niche composed of Cxcl12(+) endothelium and Wnt5a-producing Cxcr4(+) innate lymphoid cells. In diffuse-type gastric cancer this perivascular stem cell niche is expanded and can be exploited for cancer therapy.

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