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Comment
. 2016 Jan;89(1):16-9.
doi: 10.1016/j.kint.2015.11.004.

Bone strength: more than just bone density

Susan M Ott  1
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Bone strength: more than just bone density

Susan M Ott. Kidney Int. 2016 Jan.
Free article

Abstract

The following bone density measurements have limited utility in determining bone strength because they do not include bone quality: microarchitecture, mineralization, ability to repair damage, collagen structure, crystal size, or marrow composition. Patients with kidney disease have poor bone quality. Newman et al. now describe beneficial effects with raloxifene in an animal model of progressive kidney disease. These biomechanical measurements will be important in the development of medications to decrease fractures in patients.

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