Differentiation of latex allergy from irritant contact dermatitis

Abstract

The term latex allergy refers to a hypersensitivity to products containing natural rubber latex. Individuals with true latex allergy have developed type I (immediate) hypersensitivity due to previous sensitization and production of immunoglobulin E antibodies. Other forms of adverse reactions to latex-containing products may develop, including irritant contact dermatitis and type IV (delayed) hypersensitivity reactions, although they do not indicate true latex allergy. Several diagnostic tests are available to differentiate true latex allergy from irritant contact dermatitis and allergic contact dermatitis. It is crucial to determine the type of hypersensitivity in patients labeled with "latex allergy" in order to establish the most effective treatment regimen.