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Review
. 1989 Sep;36(3):178-82.
doi: 10.1111/j.1399-0004.1989.tb03185.x.

The contribution of HLA to rheumatoid arthritis

Affiliations
Review

The contribution of HLA to rheumatoid arthritis

C M Deighton et al. Clin Genet. 1989 Sep.

Abstract

The contribution of genes within the major histocompatibility complex to rheumatoid arthritis has been calculated (Rotter & Landaw 1984). Separate data from hospital- and population-based studies of monozygotic twin concordance rates and sibling recurrence risks have been used, along with material from published haplotype-sharing studies. Using either source of information gives the same result, a contribution of 37%.

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