Comment
doi: 10.1016/j.chom.2015.12.015.
Autophagy Snuffs a Macrophage's Inner Fire
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- PMID: 26764592
- DOI: 10.1016/j.chom.2015.12.015
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Autophagy Snuffs a Macrophage's Inner Fire
Cell Host Microbe.
.
Free article
Abstract
Autophagy is a well-known cell-intrinsic antiviral defense mechanism. Two new studies published in this issue of Cell Host & Microbe (Lu et al., 2016; Park et al., 2016) demonstrate that deletion of autophagy in myeloid cells leads paradoxically to better control of viral infection in vivo through enhanced inflammation, leading to antiviral resistance.
Copyright © 2016 Elsevier Inc. All rights reserved.
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