Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2016 Jan 11;29(1):1-2.
doi: 10.1016/j.ccell.2015.12.009.

Parsing Myc Paralogs in Oncogenesis

Haritha Mathsyaraja  1 , Robert N Eisenman  2
Affiliations
Free article
Comment

Parsing Myc Paralogs in Oncogenesis

Haritha Mathsyaraja et al. Cancer Cell. .
Free article

Abstract

Myc and its paralog MycN are thought to be functionally redundant, but Myc- and MycN-driven medulloblastomas exhibit distinct phenotypes. In this issue of Cancer Cell, Vo and colleagues (2016) show that this phenotypic difference stems from the preferential ability of Myc, relative to MycN, to bind Miz1 and repress transcription.

PubMed Disclaimer

Comment on

MeSH terms

Substances

LinkOut - more resources