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Observational Study
. 2016 Feb 2;114(3):340-7.
doi: 10.1038/bjc.2015.428. Epub 2016 Jan 14.

Trends in UK regional cancer mortality 1991-2007

Dominic C Marshall  1 , Thomas E Webb  1 , Richard A Hall  1 , Justin D Salciccioli  1 , Raghib Ali  2 , Mahiben Maruthappu  3
Affiliations
Observational Study

Trends in UK regional cancer mortality 1991-2007

Dominic C Marshall et al. Br J Cancer. .

Abstract

Background: Until 1990, there was an upward trend in mortality from breast, lung, prostate, and colon cancers in the United Kingdom. With improvements in cancer treatment there has, in general, been a fall in mortality over the last 20 years. We evaluate regional cancer mortality trends in the United Kingdom between 1991 and 2007.

Methods: We analysed mortality trends for breast, lung, prostate, and colon cancers using data obtained from the EUREG cancer database. We have described changes in age-standardised rates (using European standard population) per 100,000 for cancer mortality and generated trends in mortality for the 11 regions using Joinpoint regression.

Results: Across all regions in the United Kingdom there was a downward trend in mortality for the four most common cancers in males and females. Overall, deaths from colon cancer decreased most rapidly and deaths from prostate cancer decreased at the slowest rate. Similar downward trends in mortality were observed across all regions of the United Kingdom with the data for lung cancer exhibiting the greatest variation.

Conclusions: Mortality from the four most common cancers decreased across all regions of the United Kingdom; however, the rate of decline varied between cancer type and in some instances by region.

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Figures

Figure 1
Figure 1
Cancer mortality per 100 000 person-years age standardised to European standard population for colon, lung, breast, and prostate cancers across 11 regions of the United Kingdom, 1991–2007.
Figure 2
Figure 2
Trends in age-standardised (European) mortality rates from colon cancer across 11 regions of the United Kingdom, 1991–2007. Circles represent men, all ages; triangles represent women, all ages.
Figure 3
Figure 3
Trends in age-standardised (European) mortality rates from lung cancer across 11 regions of the United Kingdom, 1991–2007. Circles represent men, all ages; triangles represent women, all ages.
Figure 4
Figure 4
Trends in age-standardised (European) mortality rates from breast cancer across 11 regions of the United Kingdom, 1991–2007. Circles represents women, all ages.
Figure 5
Figure 5
Trends in age-standardised (European) mortality rates from prostate cancer across 11 regions of the United Kingdom, 1991–2007. Circles represent men, all ages.
See this image and copyright information in PMC

References

    1. Alderson M (1976) An Introduction to Epidemiology. MacMillan Press Ltd.: London. p 21.
    1. Allemani C, Weir HK, Carreira H, Harewood R, Spika D, Wang X-S, Bannon F, Ahn JV, Johnson CJ, Bonaventure A (2015) Global surveillance of cancer survival 1995–2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2). Lancet 385: 977–1010. - PMC - PubMed
    1. Autier P, Boniol M, LaVecchia C, Vatten L, Gavin A, Héry C, Heanue M (2010) Disparities in breast cancer mortality trends between 30 European countries: retrospective trend analysis of WHO mortality database. BMJ 341: c3620. - PMC - PubMed
    1. Bernie T, Les I, Paul G, Jan K, David W, Chris S (1998) A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult. BMJ 317: 559–565. - PMC - PubMed
    1. Bosetti C, Bertuccio P, Malvezzi M, Levi F, Chatenoud L, Negri E, La Vecchia C (2013) Cancer mortality in Europe, 2005-2009, and an overview of trends since 1980. Ann Oncol 24: 2657–2671. - PubMed

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