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. 2014 Mar;5(2):179-83.
doi: 10.1111/1759-7714.12056. Epub 2014 Mar 3.

Case of invasive mucinous adenocarcinoma mimicking chronic eosinophilic pneumonia

Jong Wook Beom  1 , Jong Hoo Lee  1
Affiliations

Case of invasive mucinous adenocarcinoma mimicking chronic eosinophilic pneumonia

Jong Wook Beom et al. Thorac Cancer. 2014 Mar.

Abstract

Invasive mucinous carcinoma is difficult to distinguish from other lung diseases; therefore, confirmation of the diagnosis may be delayed. A 64-year-old woman was admitted with a six-month history of cough, febrile sensation, and shortness of breath, with worsening symptoms. A computed tomography scan of the chest revealed bilateral homogenous ground-glass opacities and consolidation with subpleural predominance. The percentage of eosinophils in the serum and induced sputum was elevated and a diagnosis of chronic eosinophilic pneumonia was established. Despite administration of a systemic steroid, she did not rapidly respond. We performed a percutaneous needle biopsy and finally confirmed invasive mucinous adenocarcinoma.

Keywords: Adenocarcinoma; bronchiolo-alveolar; chronic eosinophilic pneumonia; mucinous.

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Figures

Figure 1
Figure 1
Chest radiography shows multiple nodular infiltration of the entire lung with bilateral costophrenic angle blunting.
Figure 2
Figure 2
Chest tomography reveals lobular consolidation and ground-glass attenuation with crazy-paving appearance and subpleural dominance in both lung fields (a–d). (d) Dense peribronchial consolidation in the left lower lobe.
Figure 3
Figure 3
Microscopic examination at a magnification of ×400 shows mucinous tumor cells consisting of tall columnar cells with abundant apical mucin, which had lepidic growth.
Figure 4
Figure 4
Two-[fluorine-18] Fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) imaging reveals multiple consolidative lesions in both lungs without FDG uptake.
See this image and copyright information in PMC

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