Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Jan 15:14:16.
doi: 10.1186/s12967-016-0773-4.

Translational research-the need of a new bioethics approach

Sorin Hostiuc  1   2   3 , Alin Moldoveanu  4 , Maria-Iuliana Dascălu  5 , Runar Unnthorsson  6 , Ómar I Jóhannesson  7 , Ioan Marcus  8
Affiliations
Review

Translational research-the need of a new bioethics approach

Sorin Hostiuc et al. J Transl Med. .

Abstract

Translational research tries to apply findings from basic science to enhance human health and well-being. Many phases of the translational research may include non-medical tasks (information technology, engineering, nanotechnology, biochemistry, animal research, economy, sociology, psychology, politics, and so on). Using common bioethics principles to these areas might sometimes be not feasible, or even impossible. However, the whole process must respect some fundamental, moral principles. The purpose of this paper is to argument the need for a different approach to the morality in translational bioethics, and to suggest some directions that might be followed when constructing such a bioethics. We will show that a new approach is needed and present a few ethical issues that are specific to the translational research.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Translational research—from fundamental research to developing policies (based on information retrieved from [61] and [3])
See this image and copyright information in PMC

References

    1. Sunderland M, Nayak R. Reengineering biomedical translational research with engineering ethics. Sci End Ethics. 2014. (Epub ahead of print). - PubMed
    1. Woolf SH. The meaning of translational research and why it matters. JAMA. 2008;299(2):211–213. doi: 10.1001/jama.2007.26. - DOI - PubMed
    1. Waldman SA, Terzic A. Clinical and translational science: from bench-bedside to global village. Clin Transl Sci. 2010;3(5):254–257. doi: 10.1111/j.1752-8062.2010.00227.x. - DOI - PMC - PubMed
    1. King SB. Angioplasty from bench to bedside to bench. Circulation. 1996;93(9):1621–1629. doi: 10.1161/01.CIR.93.9.1621. - DOI - PubMed
    1. Schumann K, Lin S, Boyer E, Simeonov DR, Subramaniam M, Gate RE, et al. Generation of knock-in primary human T cells using Cas9 ribonucleoproteins. Proc Natl Acad Sci. 2015;112(33):10437–10442. doi: 10.1073/pnas.1512503112. - DOI - PMC - PubMed

Publication types

LinkOut - more resources