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Review
. 2016 Jan;31(1):15-29.
doi: 10.3904/kjim.2016.31.1.15. Epub 2015 Dec 28.

Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?

Wing Wai Yew  1 , Won-Jung Koh  2
Affiliations
Review

Emerging strategies for the treatment of pulmonary tuberculosis: promise and limitations?

Wing Wai Yew et al. Korean J Intern Med. 2016 Jan.

Abstract

A worsening scenario of drug-resistant tuberculosis has increased the need for new treatment strategies to tackle this worldwide emergency. There is a pressing need to simplify and shorten the current 6-month treatment regimen for drug-susceptible tuberculosis. Rifamycins and fluoroquinolones, as well as several new drugs, are potential candidates under evaluation. At the same time, treatment outcomes of patients with drug-resistant tuberculosis should be improved through optimizing the use of fluoroquinolones, repurposed agents and newly developed drugs. In this context, the safety and tolerance of new therapeutic approaches must be addressed.

Keywords: Drug resistance; Therapeutics; Tuberculosis.

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Conflict of interest statement

WWY is a consultant to Otsuka Pharmaceutical Co. Ltd.

Figures

Figure 1.
Figure 1.
Potential candidates for a reduced 6-month treatment duration of drug-susceptible tuberculosis.
See this image and copyright information in PMC

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