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Review
. 2016 Jan;68(1):96-109.
doi: 10.1111/his.12796.

Ductal carcinoma in situ - update on risk assessment and management

Jia-Min B Pang  1   2 , Kylie L Gorringe  2   3   4 , Stephen B Fox  1   2   3
Affiliations
Review

Ductal carcinoma in situ - update on risk assessment and management

Jia-Min B Pang et al. Histopathology. 2016 Jan.

Abstract

Ductal carcinoma in situ (DCIS) accounts for ~20-25% of breast cancers. While DCIS is not life-threatening, it may progress to invasive carcinoma over time, and treatment intended to prevent invasive progression may itself cause significant morbidity. Accurate risk assessment is therefore necessary to avoid over- or undertreatment of an individual patient. In this review we will outline the evidence for current management of DCIS, discuss approaches to DCIS risk assessment and challenges facing identification of novel DCIS biomarkers.

Keywords: breast neoplasms; clinical markers; clinical pathology; patient care management.

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