Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan 15;14(1):11.
doi: 10.1186/s12957-015-0765-5.

Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series

Affiliations

Surgery for retrohepatic caval thrombus in patients with advanced renal cell carcinoma: a case series

Małgorzata Polańska-Płachta et al. World J Surg Oncol. .

Abstract

Background: Thrombotic involvement of the inferior vena cava (IVC) occurs in about 10% of all patients with renal cell carcinoma (RCC). It is treated with radical resection of tumor and thrombus. We present the results of a recent case series of 20 patients with retrohepatic IVC thrombus.

Methods: Our cohort of 20 patients included 16 primary resections (radical nephrectomy and thrombectomy with and without vascular graft), three recurrences primarily operated on elsewhere (thrombectomy and vascular graft), and one recurrence due to a new liver metastasis.

Results: All surviving patients were discharged with a patent IVC. The overall mortality rate was 10%, and the overall complication rate was 35%. Both are in keeping with results presented worldwide.

Conclusions: Our series provides a corroborating extension to the existing dataset on RCC-related IVC thrombus removal. It confirms that the radical surgical approach can be performed safely and successfully with respect to venous patency.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Left renal vein totally occluded by neoplastic thrombus. a Wall of the renal vein. b Neoplastic thrombus
Fig. 2
Fig. 2
Retrohepatic inferior vena cava (IVC) closed with aid of a Dacron® graft
Fig. 3
Fig. 3
Neoplastic thrombus removed from IVC. a Neoplastic thrombus. b Kidney with neoplasm

References

    1. Mootha RK, Butler R, Laucirica R, Scardino PT, Lerner SP. Renal cell carcinoma with an infrarenal vena caval tumor thrombus. Urology. 1999;54:561. doi: 10.1016/S0090-4295(99)00136-3. - DOI - PubMed
    1. Kirkali Z, Van Poppel H. A critical analysis of surgery for kidney cancer with vena cava invasion. Eur Urol. 2007;52:658–662. doi: 10.1016/j.eururo.2007.05.009. - DOI - PubMed
    1. Nouh MA, Inui M, Kakehi Y. Renal cell carcinoma with IVC thrombi; current concepts and future perspectives. Clin Med Oncol. 2008;2:247–256. - PMC - PubMed
    1. Sidana A, Goyal J, Aggarwal P, Verma P, Rodriguez R. Determinants of outcomes after resection of renal cell carcinoma with venous involvement. Int Urol Nephrol. 2012;44:1671–1679. doi: 10.1007/s11255-012-0314-x. - DOI - PubMed
    1. Nesbitt JC, Soltero ER, Dinney CP, Walsh GL, Schrump DS, Swanson DA, et al. Surgical management of renal cell carcinoma with inferior vena cava tumor thrombus. Ann Thorac Surg. 1997;63:1592–1600. doi: 10.1016/S0003-4975(97)00329-9. - DOI - PubMed