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. 2015:2015:959876.
doi: 10.1155/2015/959876. Epub 2015 Dec 6.

Conservative Management of Cesarean Scar Ectopic Pregnancy with Fetal Heart Activity and a Very High β-hCG

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Conservative Management of Cesarean Scar Ectopic Pregnancy with Fetal Heart Activity and a Very High β-hCG

Rodney McLaren et al. Case Rep Obstet Gynecol. 2015.

Abstract

Cesarean scar ectopic pregnancy (CSP) is a rare type of ectopic pregnancy that is growing in incidence. The diagnosis of most CSP occurs when patients present in unstable conditions requiring surgical management and leading sometimes to hysterectomy. It has been shown that medical management is a safe option for early diagnosed hemodynamically stable CSP. However, no cases of CSP with β-hCG higher than 62,000 IU/L, conservatively treated, have been reported. We report the case of a 29-year-old patient who presented for her first prenatal visit at 13-week gestation and was diagnosed with CSP with present fetal heart tones and a quantitative β-hCG of 144,337 IU/L. She was treated with bilateral uterine artery embolization and systemic methotrexate. Her β-hCG significantly decreased and became undetectable within 10 weeks. We propose that patients with CSP with very high β-hCG and fetal heart activity can be offered conservative or fertility preserving management.

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Figures

Figure 1
Figure 1
Transvaginal ultrasound showing cesarean scar ectopic pregnancy with placental circulation seen on color Doppler.
Figure 2
Figure 2
Transvaginal ultrasound showing fetus before treatment (a) and 7 days following uterine artery embolization and systemic methotrexate (b).
Figure 3
Figure 3
Graph depicting the trend of serum β-hCG level following uterine artery embolization and systemic methotrexate.

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References

    1. Rotas M. A., Haberman S., Levgur M. Cesarean scar ectopic pregnancies: etiology, diagnosis, and management. Obstetrics and Gynecology. 2006;107(6):1373–1381. doi: 10.1097/01.aog.0000218690.24494.ce. - DOI - PubMed
    1. Jurkovic D., Hillaby K., Woelfer B., Lawrence A., Salim R., Elson C. J. First-trimester diagnosis and management of pregnancies implanted into the lower uterine segment Cesarean section scar. Ultrasound in Obstetrics and Gynecology. 2003;21(3):220–227. doi: 10.1002/uog.56. - DOI - PubMed
    1. Maymon R., Halperin R., Mendlovic S., Schneider D., Herman A. Ectopic pregnancies in a caesarean scar: review of the medical approach to an iatrogenic complication. Human Reproduction Update. 2004;10(6):515–523. doi: 10.1093/humupd/dmh042. - DOI - PubMed
    1. Sugawara J., Senoo M., Chisaka H., Yaegashi N., Okamura K. Successful conservative treatment of a cesarean scar pregnancy with uterine artery embolization. The Tohoku Journal of Experimental Medicine. 2005;206(3):261–265. doi: 10.1620/tjem.206.261. - DOI - PubMed
    1. Li N., Zhu F., Fu S., Shi X. Transvaginal ultrasound-guided embryo aspiration plus local administration of low-dose methotrexate for caesarean scar pregnancy. Ultrasound in Medicine and Biology. 2012;38(2):209–213. doi: 10.1016/j.ultrasmedbio.2011.10.012. - DOI - PubMed

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