Is interferon tissue specific?- Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines
- PMID: 267737
- DOI: 10.1099/0022-1317-35-3-573
Is interferon tissue specific?- Effect of human leukocyte and fibroblast interferons on the growth of lymphoblastoid and osteosarcoma cell lines
Abstract
The growth inhibitory effect of human leukocyte and fibroblast interferons was tested in vitro. The effect of fibroblast interferon was more pronounced on osteosarcoma cells and the effect of leukocyte interferon was more pronounced on lymphoid cells. This suggests that the capacity of interferon to inhibit cell growth is, in some measure, tissue specific.
Similar articles
-
Comparison of the suppression of cell and virus growth in transformed human cells of leukocyte and fibroblast interferon.J Gen Virol. 1979 May;43(2):435-9. doi: 10.1099/0022-1317-43-2-435. J Gen Virol. 1979. PMID: 225426
-
Effects of leukocyte and fibroblast interferon on events in the fibroblast cell cycle.J Gen Virol. 1979 Mar;42(3):589-95. doi: 10.1099/0022-1317-42-3-589. J Gen Virol. 1979. PMID: 430031
-
Sensitivity of various human lymphoblastoid cells to the antiviral and anticellular activity of human leukocyte interferon.Arch Virol. 1977;54(3):271-7. doi: 10.1007/BF01314795. Arch Virol. 1977. PMID: 407887
-
Biological properties of virus-induced interferons.Tex Rep Biol Med. 1977;35:11-6. Tex Rep Biol Med. 1977. PMID: 80828 Review.
-
Production of human interferons: an overview.Dev Biol Stand. 1983;55:219-30. Dev Biol Stand. 1983. PMID: 6203796 Review.
Cited by
-
Differential serum interferon-β levels in autoimmune thyroid diseases.Arch Med Sci. 2021 Jan 31;18(5):1231-1240. doi: 10.5114/aoms/110164. eCollection 2022. Arch Med Sci. 2021. PMID: 36160354 Free PMC article.
-
Comparison of antiviral activities of cloned and native human interferons against herpes simplex virus types 1 and 2 and human cytomegalovirus.Antimicrob Agents Chemother. 1984 Oct;26(4):599-600. doi: 10.1128/AAC.26.4.599. Antimicrob Agents Chemother. 1984. PMID: 6097170 Free PMC article.
-
Management of osteosarcoma.Curr Treat Options Oncol. 2006 Nov;7(6):444-55. doi: 10.1007/s11864-006-0020-y. Curr Treat Options Oncol. 2006. PMID: 17032557 Review.
-
Current therapeutic strategies and novel approaches in osteosarcoma.Cancers (Basel). 2013 May 24;5(2):591-616. doi: 10.3390/cancers5020591. Cancers (Basel). 2013. PMID: 24216993 Free PMC article.
-
Human leukocyte and fibroblast interferon in a combination therapy of dendritic keratitis.Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Nov 30;208(4):229-33. doi: 10.1007/BF00419377. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978. PMID: 310269 Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources