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. 2016 Feb;39(2):51-53.
doi: 10.1016/j.tins.2015.12.010. Epub 2016 Jan 6.

Fight, Flight, or Freeze? The Answer May Depend on Your Sex

Carolyn E Jones  1 , Marie-H Monfils  2
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Fight, Flight, or Freeze? The Answer May Depend on Your Sex

Carolyn E Jones et al. Trends Neurosci. 2016 Feb.

Abstract

Pavlovian fear conditioning is one of the most common and well-understood methods for studying fear learning. However, research is predominantly performed in males. Recently, in a classical Pavlovian fear conditioning paradigm, Gruene and colleagues described an active conditioned fear response ('darting') prevalent in female rats that better maintain an extinction memory.

Keywords: escape; fear conditioning; females; sex differences.

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