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. 2016 Feb 1;26(3):799-803.
doi: 10.1016/j.bmcl.2015.12.091. Epub 2015 Dec 28.

Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng

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Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng

Qin-Ge Ma et al. Bioorg Med Chem Lett. .

Abstract

Four new alkenes (1-4), and six known alkenes (5-12) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1-12) were evaluated for antioxidative activities. Among them, compounds 1, 2, 4, and 7 exhibited significant antioxidative activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay with IC50=21.4-49.5 μM. The known compounds (5-12) were isolated from this plant for the first time.

Keywords: Alkene; Antioxidative activity; Murraya koenigii.

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