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Review
. 2016 Apr;65(2):123-126.
doi: 10.1016/j.alit.2015.12.001. Epub 2016 Jan 8.

Does epigenetics play a role in human asthma?

Donata Vercelli  1
Affiliations
Free article
Review

Does epigenetics play a role in human asthma?

Donata Vercelli. Allergol Int. 2016 Apr.
Free article

Abstract

Asthma and other allergic diseases are among the most prevalent chronic non-communicable diseases of childhood. According to the World Health Organization, asthma affects >7.0 million children under 18 in the United States, with an economic burden that is estimated to exceed that of tuberculosis and HIV/AIDS combined. Despite much research, the natural history of asthma and its pathogenesis are still in many ways elusive. This review discusses our current understanding of the role epigenetic processes play in asthma pathogenesis, focusing on genome-wide, population-based studies.

Keywords: Allergy; Birth cohort; Childhood asthma; DNA methylation; Epigenetics.

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