Genetic engineering: In vivo genome editing - growing in strength

Editorial

Linda Koch. Nat Rev Genet. 2016 Mar.

. 2016 Mar;17(3):124.

doi: 10.1038/nrg.2016.2. Epub 2016 Jan 19.

No abstract available

Comment on

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.
Long C, Amoasii L, Mireault AA, McAnally JR, Li H, Sanchez-Ortiz E, Bhattacharyya S, Shelton JM, Bassel-Duby R, Olson EN. Long C, et al. Science. 2016 Jan 22;351(6271):400-3. doi: 10.1126/science.aad5725. Epub 2015 Dec 31. Science. 2016. PMID: 26721683 Free PMC article.
In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.
Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Castellanos Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. Nelson CE, et al. Science. 2016 Jan 22;351(6271):403-7. doi: 10.1126/science.aad5143. Epub 2015 Dec 31. Science. 2016. PMID: 26721684 Free PMC article.
In vivo gene editing in dystrophic mouse muscle and muscle stem cells.
Tabebordbar M, Zhu K, Cheng JKW, Chew WL, Widrick JJ, Yan WX, Maesner C, Wu EY, Xiao R, Ran FA, Cong L, Zhang F, Vandenberghe LH, Church GM, Wagers AJ. Tabebordbar M, et al. Science. 2016 Jan 22;351(6271):407-411. doi: 10.1126/science.aad5177. Epub 2015 Dec 31. Science. 2016. PMID: 26721686 Free PMC article.