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. 2015:2015:819194.
doi: 10.1155/2015/819194. Epub 2015 Dec 13.

Chronic Comorbidities Contribute to the Burden and Costs of Persistent Asthma

Paula Kauppi  1 , Miika Linna  2 , Juha Jantunen  3 , Jaana E Martikainen  4 , Tari Haahtela  1 , Anna Pelkonen  5 , Mika Mäkelä  5
Affiliations

Chronic Comorbidities Contribute to the Burden and Costs of Persistent Asthma

Paula Kauppi et al. Mediators Inflamm. 2015.

Abstract

Background: We aimed to study the prevalence of chronic comorbidities in asthma patients and the costs of health care use associated with asthma with comorbidities.

Material and methods: We analysed the prevalence of the four most common chronic diseases in asthma patients in 2008-2014 in Finland. Prevalence of coronary artery disease, diabetes and dyslipidaemia, hypertension, epilepsy, inflammatory bowel disease, rheumatic diseases, and severe psychiatric disease was studied by register of the Social Insurance Institution of Finland. The costs of health care services were collected from the registries maintained by the National Institute for Health and Welfare (THL).

Results: Prevalence of asthma was 4.6% in 2014. Diabetes was among the four most common comorbidities in all the age groups. The other common comorbidities were hypertension (≥46 years; 12.9-37.6%), severe psychiatric disorders (age groups of 16-59 years; 1.4-3.5%), and ischaemic heart disease (≥60 years; 10-25%). In patients with both asthma and diabetes, the costs of hospitalization were approximately 169% compared with patients with asthma alone.

Conclusions: Prevalence of asthma increases by tenfold when aging. The comorbidity diversity and rate are age-dependent. Prevalence of diabetes as comorbidity in asthma has increased. Costs of hospitalizations in asthma approximately double with chronic comorbidities.

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Figures

Figure 1
Figure 1
Proportion of asthmatics in different age groups and proportion of the age group of total population in 2014.
Figure 2
Figure 2
Four most common comorbidities among patients with persistent asthma in different age groups according to Social Insurance Institution register data from 2008 to 2014 (from top and light grey to bottom and dark green of a bar).
Figure 3
Figure 3
Number and distribution of asthma and diabetes patients according to age.
See this image and copyright information in PMC

References

    1. Haahtela T., Tuomisto L. E., Pietinalho A., et al. A 10 year asthma programme in Finland: major change for the better. Thorax. 2006;61(8):663–670. doi: 10.1136/thx.2005.055699. - DOI - PMC - PubMed
    1. Haahtela T., Valovirta E., Kauppi P., et al. The finnish allergy programme 2008–2018—scientific rationale and practical implementation. Asia Pacific Allergy. 2012;2(4):275–279. doi: 10.5415/apallergy.2012.2.4.275. - DOI - PMC - PubMed
    1. Chung K. F., Wenzel S. E., Brozek J. L., et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. European Respiratory Journal. 2014;43(2):343–373. doi: 10.1183/09031936.00202013. - DOI - PubMed
    1. Hasegawa K., Tsugawa Y., Brown D. F. M., Camargo C. A., Jr. A population-based study of adults who frequently visit the emergency department for acute asthma. California and Florida, 2009-2010. Annals of the American Thoracic Society. 2014;11(2):158–166. doi: 10.1513/annalsats.201306-166oc. - DOI - PubMed
    1. Kauppi P., Linna M., Martikainen J., Mäkelä M. J., Haahtela T. Follow-up of the Finnish Asthma Programme 2000–2010: reduction of hospital burden needs risk group rethinking. Thorax. 2013;68(3):292–293. doi: 10.1136/thoraxjnl-2011-201028. - DOI - PubMed

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