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Case Reports
. 2015 Dec 1;4(1):90-4.
doi: 10.1002/ccr3.449. eCollection 2016 Jan.

A case of primary biliary cirrhosis in a patient with rheumatoid arthritis

Norifumi Bekki  1 , Sung Kwan Bae  1 , Seiji Yoshizawa  2 , Ayaka Shiota  1 , Toshifumi Gushima  1 , Junichi Motoshita  3 , Shinji Shimoda  4 , Yoshihiro Aiba  5 , Atsumasa Komori  5 , Minoru Nakamura  5 , Kazuhiro Takahashi  1
Affiliations
Case Reports

A case of primary biliary cirrhosis in a patient with rheumatoid arthritis

Norifumi Bekki et al. Clin Case Rep. .

Abstract

The true prevalence of PBC in RA is not well known. Herein, we report an unusual case of a patient with PBC and RA, and discuss the association between these two diseases. PBC should be ruled out in the differential diagnosis of patients with RA having abnormal liver function tests.

Keywords: Genome‐wide association studies; primary biliary cirrhosis; rheumatoid arthritis; ursodeoxycholic acid.

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Figures

Figure 1
Figure 1
The clinical course of the patient.
Figure 2
Figure 2
(A) A liver biopsy at day 4. Marked inflammatory cell infiltration is observed surrounding and destroying the interlobular bile ducts with ductular proliferation in the portal area. (B) A liver biopsy at day 445. The infiltration of inflammatory cells in the portal area is markedly improved.
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