Location, Location, Location: Localized Memory Cells Take Residence in the Allergic Lung
- PMID: 26789918
- DOI: 10.1016/j.immuni.2015.12.012
Location, Location, Location: Localized Memory Cells Take Residence in the Allergic Lung
Abstract
Understanding the localization of cells is important as local environmental cues influence both phenotype and effector function. In this issue of Immunity, Pepper and colleagues find that allergen-specific tissue-resident memory T cells are maintained by IL-2 and are key drivers of allergic pathology.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Interleukin-2-Dependent Allergen-Specific Tissue-Resident Memory Cells Drive Asthma.Immunity. 2016 Jan 19;44(1):155-166. doi: 10.1016/j.immuni.2015.11.004. Epub 2015 Dec 29. Immunity. 2016. PMID: 26750312 Free PMC article.
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