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Review
. 2015 Dec;7(12):2188-93.
doi: 10.3978/j.issn.2072-1439.2015.11.01.

The future of left ventricular assist devices

Ahmet Kilic  1
Affiliations
Review

The future of left ventricular assist devices

Ahmet Kilic. J Thorac Dis. 2015 Dec.

Abstract

The widespread acceptance of left ventricular assist device (LVAD) implantation in the treatment of heart failure has revolutionized the way end stage heart failure is treated. Advances in LVAD technology combined with a better understanding of patient selection has led to unparalleled survival as well as a reduction in the adverse event profile of these pumps. As our understanding of heart failure continues to grow, there is little doubt that LVADs will continue to play a pivotal role as a therapeutic option for those suffering from heart failure.

Keywords: Left ventricular assist device (LVAD); mechanical circulatory support (MCS).

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Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Patient and hospital primary implantation of permanent mechanical circulatory support devices participating in the INTERMACS registry between June 23, 2006 and December 31, 2013. There are a total of 10,542 primary implanted patients and 141 active hospitals.
Figure 2
Figure 2
Hazard unction for mortality following primary implantation for continuous-flow devices broken down by causative mortality between 2008 to 2013 in the INTERMACS registry. RHF, right heart failure; MSOF, multi-system organ failure; LVAD, left ventricular assist device; BiVAD, bi-ventricular assist device; INTERMACS, interagency for mechanically assisted circulatory support.
See this image and copyright information in PMC

References

    1. Kantrowitz A, Tjonneland S, Freed PS, et al. Initial clinical experience with intraaortic balloon pumping in cardiogenic shock. JAMA 1968;203:113-8. - PubMed
    1. Kilic A, Ailawadi G. Left ventricular assist devices in heart failure. Expert Rev Cardiovasc Ther 2012;10:649-56. - PubMed
    1. Barnard CN. The operation. A human cardiac transplant: An interim report of a successful operation performed at Groote Schuur Hospital, Cape Town. S Afr Med J 1967;41:1271-4. - PubMed
    1. Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med 2001;345:1435-43. - PubMed
    1. Kirklin JK, Naftel DC, Pagani FD, et al. Sixth INTERMACS annual report: A 10,000-patient database. J Heart Lung Transplant 2014;33:555-64. - PubMed