Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;53(6):785-8.
doi: 10.3347/kjp.2015.53.6.785. Epub 2015 Dec 31.

Surgical and Molecular Evaluation of Pediatric Hydatid Cyst Cases in Eastern Turkey

Unal Bakal  1 , Sami Simsek  2 , Ahmet Kazez  1
Affiliations

Surgical and Molecular Evaluation of Pediatric Hydatid Cyst Cases in Eastern Turkey

Unal Bakal et al. Korean J Parasitol. 2015 Dec.

Abstract

Cystic echinococcosis (CE) caused by Echinococcus granulosus is a major public health problem worldwide, including Turkey. The aim of the current study was to identify the strains and to estimate the potential risk factors of E. granulosus in operated pediatric cases in eastern Turkey. Ten pediatric patients (7 boys and 3 girls) living in rural areas, with ages ranging from 3 to 15 years old and various clinical histories, were included in this study. Eight patients had only liver hydatid cyst, while 1 patient had liver and lung hydatid cyst and the other liver, lung, and spleen, together. There were 2 ruptured liver cysts. After surgery, during follow-up, no increase was observed in hemagglutination levels, there were no mortalities, and there was no evidence of recurrence at 2 years post operation in all patients. Molecular analysis was performed on hydatid cyst samples obtained from the 10 pediatric cases. According to mt-12S rRNA PCR results, all cases were found to be G1/G3 cluster of E. granulosus sensu stricto.

Keywords: Hydatid cyst; PCR; Turkey; pediatric surgery; risk factor.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they do not have any conflict of interest.

References

    1. Thompson RCA. Biology and systematics of Echinococcus. In: Thompson RCA, Lymbery AJ, editors. Echinococcus and hydatid disease. Wallingford, UK: CAB International; 1995. pp. 1–50.
    1. Grosso G, Gruttadauria S, Biondi A, Marventano S, Mistretta A. Worldwide epidemiology of liver hydatidosis including the Mediterranean area. World J Gastroenterol. 2012;18:1425–1437. - PMC - PubMed
    1. Craig PS, McManus DP, Lightowlers MW, Chabalgoity JA, Garcia HH, Gavidia CM, Gilman RH, Gonzalez AE, Lorca M, Naquira C, Nieto A, Schantz PM. Prevention and control of cystic echinococcosis. Lancet Infect Dis. 2007;7:385–394. - PubMed
    1. Bryan RT, Schantz PM. Echinococcosis (hydatid disease) J Am Vet Med Assoc. 1989;195:1214–1217. - PubMed
    1. Bakal U, Kazez A, Akyol M, Kocakoc E, Simsek S. A portable ultrasound based screening study on the prevalence and risk factors of Cystic Echinococcosis in primary school children in east Turkey. Acta Tropica. 2012;123:91–95. - PubMed

LinkOut - more resources