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. 2015 Oct-Dec;7(4):22-33.

Survival guide: Escherichia coli in the stationary phase

P Pletnev  1 , I Osterman  1 , P Sergiev  1 , A Bogdanov  1 , O Dontsova  1
Affiliations

Survival guide: Escherichia coli in the stationary phase

P Pletnev et al. Acta Naturae. 2015 Oct-Dec.

Abstract

This review centers on the stationary phase of bacterial culture. The basic processes specific to the stationary phase, as well as the regulatory mechanisms that allow the bacteria to survive in conditions of stress, are described.

Keywords: Escherichia coli; starvation; stationary phase; stress; survival.

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Figures

Fig. 1
Fig. 1
Bacterial growth curve. 1 – lag-phase, 2 – logarithmic phase, 3 – stationary phase, 4 – death phase, 5 – long-term stationary phase
Fig. 2
Fig. 2
Normalized (H-NS, Fis, HU, IHF – dimers, Dps – dodecamers) amounts of structural nucleoid proteins during different growth phases. Based on data from [5]
Fig. 3
Fig. 3
Regulation of σ38 expression and activity. The upper left side of the figure shows the regulation of σ38 (rpoS) gene transcription. Effect of transcription regulatory proteins shown by arrows. The right-hand part of the figure illustrates the effect of the H-NS protein and DsrA RNA on the secondary structure of rpoS mRNA. Shine-Dalgarno sequence designated as “S.-D.”, open read frame designated as ORF. Proteins affecting the translation of rpoS mRNA are shown in the center of the picture. Proteins affecting the stability of σ38-protein are shown in the lower part of the picture
Fig. 4
Fig. 4
Scheme of RelA-dependent synthesis of ppGpp during amino acid starvation
Fig. 5
Fig. 5
Binding sites of the hibernation factors RMF (PDB: 4V8G), HPF (PDB: 4V8H), and YfiA (PDB: 4V8I)
See this image and copyright information in PMC

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