Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Apr;37(4):1512-3.
doi: 10.1002/hbm.23116. Epub 2016 Jan 23.

Altered short-term plasticity within the working memory neural network: Is it neuroticism or is it depression?

Affiliations
Review

Altered short-term plasticity within the working memory neural network: Is it neuroticism or is it depression?

Renzo Bianchi et al. Hum Brain Mapp. 2016 Apr.

Abstract

In the present article, we discuss (1) the importance of assessing and statistically considering both clinical and subclinical forms of depression when examining the relationship between neuroticism and short-term plasticity within the working memory neural network, and (2) the hypothesis of an antagonism between neuroticism and conscientiousness in personality research. We suggest that (1) neuroticism and depression should be examined in a relational manner, and (2) neuroticism and conscientiousness should not be antagonized.

Keywords: depression; fronto-parietal network; neural connectivity; neuroticism; working memory.

PubMed Disclaimer

References

    1. Beckmann N, Wood RE, Minbashian A (2010): It depends how you look at it: On the relationship between neuroticism and conscientiousness at the within‐ and the between‐person levels of analysis. J Res Pers 44:593–601.
    1. Bianchi R, Laurent E (2016): Depressive symptomatology should be systematically controlled for in neuroticism research. Neuroimage 15:1099–1100. - PubMed
    1. Buckholtz JW, Meyer‐Lindenberg A (2012): Psychopathology and the human connectome: Toward a transdiagnostic model of risk for mental illness. Neuron 74:990–1004. - PubMed
    1. Cuijpers P, Vogelzangs N, Twisk J, Kleiboer A, Li J, Penninx BW (2013): Differential mortality rates in major and subthreshold depression: Meta‐analysis of studies that measured both. Br J Psychiatry 202:22–27. - PubMed
    1. DeYoung CG, Hirsh JB, Shane MS, Papademetris X, Rajeevan N, Gray JR (2010): Testing predictions from personality neuroscience. Brain structure and the Big Five. Psychol Sci 21:820–828. - PMC - PubMed