Drinking During Pregnancy and the Developing Brain: Is Any Amount Safe?
- PMID: 26801950
- PMCID: PMC4788102
- DOI: 10.1016/j.tics.2015.09.011
Drinking During Pregnancy and the Developing Brain: Is Any Amount Safe?
Abstract
Heavy prenatal alcohol exposure can have lifelong, disabling effects on brain and cognition. Unlike animal studies, research on light-to-moderate drinking in humans demonstrates less consistent impact. Discussions of negative research findings in popular media underestimate potential adverse outcomes and complicate decisions about risks versus benefits of light-to-moderate drinking during pregnancy.
Copyright © 2015 Elsevier Ltd. All rights reserved.
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References
-
- Kable JA, et al. Neurobehavioral Disorder Associated with Prenatal Alcohol Exposure (ND-PAE): Proposed DSM-5 Diagnosis. Child Psychiatry Hum Dev 2015 - PubMed
-
- Flak AL, et al. The association of mild, moderate, and binge prenatal alcohol exposure and child neuropsychological outcomes: a meta-analysis. Alcoholism, clinical and experimental research. 2014;38:214–226. - PubMed
-
- Warren KR, Hewitt BG. Fetal alcohol spectrum disorders: when science, medicine, public policy, and laws collide. Dev Disabil Res Rev. 2009;15:170–175. - PubMed
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