A window to beyond the orbit: the value of optical coherence tomography in non-ocular disease

Abstract

Optical coherence tomography (OCT) imaging of the eye has become an essential tool for the ophthalmologist, aiding diagnosis and assisting with treatment decisions, in many ocular diseases. However, there is an evolving role for OCT in informing on non-ocular diseases, which ophthalmologists should be aware of. The purpose of this review was to examine recent evidence for the role of ocular OCT imaging to evaluate disease beyond the orbit and to discuss possible opportunities and challenges arising from this, from the perspective of the ophthalmologist.

Keywords: biomarker; glaucoma; neurodegeneration; optical coherence tomography; retinal imaging; systemic disease.