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. 2016 Feb;89(2):263-6.
doi: 10.1016/j.kint.2015.12.025.

Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: a new twist on an old tale

Madhav C Menon  1 , Michael J Ross  2
Affiliations
Free article

Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: a new twist on an old tale

Madhav C Menon et al. Kidney Int. 2016 Feb.
Free article

Abstract

Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.

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