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Review
. 2016 Jan 25;5(1):e002477.
doi: 10.1161/JAHA.115.002477.

Clinical Phenotypes in Heart Failure With Preserved Ejection Fraction

Rohan Samson  1 , Abhishek Jaiswal  1 , Pierre V Ennezat  2 , Mark Cassidy  1 , Thierry H Le Jemtel  1
Affiliations
Review

Clinical Phenotypes in Heart Failure With Preserved Ejection Fraction

Rohan Samson et al. J Am Heart Assoc. .
No abstract available

Keywords: Aging; heart failure; hypertension; obesity; preserved ejection fraction.

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Figures

Figure 1
Figure 1
Hypertension is the steadfast underpinning of heart failure with preserved ejection (HFpEF). Aging, obesity, pulmonary hypertension (PH), and coronary artery disease (CAD) affect HFpEF presentation and progression. Their presence defines 4 common phenotypes that share atrial fibrillation, anemia, chronic obstructive pulmonary disease (COPD), frailty, diabetes, obstructive sleep apnea, and chronic kidney disease (CKD) as comorbid conditions. HTN indicates hypertension.
See this image and copyright information in PMC

References

    1. Cohn JN, Johnson G. Heart failure with normal ejection fraction, the V‐HeFT study. Circulation. 1990;81(suppl III):III‐48–III‐53. - PubMed
    1. Vasan RS, Benjamin EJ, Levy D. Prevalence, clinical features and prognosis of diastolic heart failure: an epidemiologic perspective. J Am Coll Cardiol. 1995;26:1656–1674. - PubMed
    1. Zile MR, Brustaert DL. New concepts in diastolic dysfunction and diastolic heart failure. Part I diagnosis, prognosis and measurements of diastolic function. Circulation. 2002;105:1387–1393. - PubMed
    1. Zile MR, Brustaert DL. New concepts in diastolic dysfunction and diastolic heart failure: part II. Causal mechanisms and treatment. Circulation. 2002;105:1503–1508. - PubMed
    1. Kitzman DL, Little WC, Brubaker PH, Anderson RT, Hundley WG, Marbuger CT, Brosnihan B, Morgan TM, Stewart KP. Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure. JAMA. 2002;288:2144–2150. - PubMed

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