Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Nov;171(11):6025-9.
doi: 10.1128/jb.171.11.6025-6029.1989.

Participation of Escherichia coli heat shock proteins DnaJ, DnaK, and GrpE in P1 plasmid replication

K Tilly  1 , M Yarmolinsky
Affiliations

Participation of Escherichia coli heat shock proteins DnaJ, DnaK, and GrpE in P1 plasmid replication

K Tilly et al. J Bacteriol. 1989 Nov.

Abstract

Low-copy-number plasmids, such as P1 prophage and the fertility factor F, require a plasmid-encoded replication protein and several host products for replication. Stable maintenance also depends on active partitioning of plasmids into daughter cells. Mini-P1 par+ and par plasmids were found to be destabilized by mutations in the dnaJ, dnaK, and grpE genes of Escherichia coli. The transformation efficiency and stability of mini-F plasmids were also reduced in the mutant strains. These results indicate that heat shock proteins DnaJ, DnaK, and GrpE play roles in the replication of plasmid P1 and probably also in of F.

PubMed Disclaimer

References

    1. J Bacteriol. 1979 May;138(2):339-44 - PubMed
    1. J Bacteriol. 1989 Nov;171(11):6030-8 - PubMed
    1. J Bacteriol. 1979 Dec;140(3):864-73 - PubMed
    1. Mol Gen Genet. 1981;182(1):12-8 - PubMed
    1. J Bacteriol. 1983 Feb;153(2):800-12 - PubMed

Substances

LinkOut - more resources