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. 2016:20:41-5.
doi: 10.1016/j.ijscr.2016.01.008. Epub 2016 Jan 16.

Atypical breasts cancers

Lucie Wright  1 , Cho Ee Ng  2 , Tarannum Fasih  3
Affiliations

Atypical breasts cancers

Lucie Wright et al. Int J Surg Case Rep. 2016.

Abstract

Introduction: With increasing incidence of breast cancers there are now a larger number of cases diagnosed with rare malignancies. These can be diagnostic dilemmas and management strategy can be different by various breast multi-disciplinary teams (MDT). We aim to discuss the evidence-based approach for management of these atypical breast cancers which were identified in patients from a single breast screening unit.

Method: Patient with unusual breast malignancies (all types except invasive ductal and lobular) treated under the care of a single surgeon were identified during the breast multi-disciplinary discussion from 2011 to 2015. The histology and management of these cases were reviewed and literature search of electronic databases via PubMed and the search engines Google/Google Scholar was performed. Emphasis on keywords based on the histology type was used to limit search. Search was focused on the diagnosis, management and prognosis of these unusual breast cancers.

Conclusion: This series aims to focus on the evidence-based management of these rare breast malignancies; the diagnosis of which is crucial as it affects the overall treatment and prognosis.

Keywords: Apocrine carcinoma; Malignant myoepithelioma; Mucinous carcinoma; Rare breast malignancies.

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Figures

Fig. 1
Fig. 1
Malignant adenomyoepithelioma with a central component of small well-formed tubules and spindle cells, and a more atypical epithelioid component at the periphery.
Fig. 2
Fig. 2
Invasive mucinous carcinoma composed of sheets of monotonous atypical epithelial cells within dissecting pools of mucin.
Fig. 3
Fig. 3
Invasive apocrine carcinoma composed of cells with abundant eosinophilic and finely granular cytoplasm.
See this image and copyright information in PMC

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