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Review
. 1989 Nov;21(5 Pt 2):1119-22.
doi: 10.1016/s0190-9622(89)70310-8.

Granulomatous eruption after BCG vaccine immunotherapy for malignant melanoma

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Review

Granulomatous eruption after BCG vaccine immunotherapy for malignant melanoma

C R Shea et al. J Am Acad Dermatol. 1989 Nov.

Abstract

In a patient receiving intralesional bacille Calmette-Guérin vaccine injections for recurrent cutaneous metastases of malignant melanoma of the right leg, a striking eruption developed on that limb only. The eruption consisted of multiple 1 to 2 mm, reddish brown, flat-topped papules, with confluence into plaques. Histopathologic examination showed multiple tuberculoid granulomas within the papillary and reticular dermis; special stains and cultures were negative for mycobacteria.

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