Legionella effectors reflect strength in diversity
- PMID: 26813764
- DOI: 10.1038/ng.3492
Legionella effectors reflect strength in diversity
Abstract
The Legionella genus includes opportunistic human pathogenic species that invade human cells using effector proteins that evolved during association with their natural amoeba hosts. A new study compares the genomes of 41 Legionella species to identify nearly 6,000 effectors, providing insight into these species' evolution and pathogenic lifestyles.
Comment on
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Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.Nat Genet. 2016 Feb;48(2):167-75. doi: 10.1038/ng.3481. Epub 2016 Jan 11. Nat Genet. 2016. PMID: 26752266 Free PMC article.
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