Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan-Feb;29(1):37-40.
doi: 10.1111/dth.12299. Epub 2015 Nov 2.

Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients

Kui Young Park  1 , Joon Seok  1 , Nark Kyoung Rho  2 , Beom Joon Kim  1 , Myeung Nam Kim  1
Affiliations

Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients

Kui Young Park et al. Dermatol Ther. 2016 Jan-Feb.

Abstract

Aging well has become the new target of preventative medicine, and aesthetic dermatology can contribute to this request. The polynucleotide (PN) containing products not only fill the space, but improve tissue regeneration, resulting in more natural tissue regeneration. Five Korean women received four times injections of long-chain PN filler in two-week intervals for skin rejuvenation. About 0.05 mL of material was injected in 40 points of one-side cheek. The pore and skin thickness were markedly improved in the patients in their 30s, whereas skin tone, melanin, wrinkles, and sagging were noticeably improved for patients in their 40s. There are no serious side effects. In conclusion, intradermal long-chain PN filler injection seems to be an effective and safe treatment for skin rejuvenation.

Keywords: filler; polynucleotide; skin rejuvenation.

PubMed Disclaimer