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Review
. 2015 Jun;4(3):381-90.
doi: 10.3978/j.issn.2223-4683.2015.06.02.

Advances in the treatment of testicular cancer

Yaron Ehrlich  1 , David Margel  1 , Marc Alan Lubin  1 , Jack Baniel  1
Affiliations
Review

Advances in the treatment of testicular cancer

Yaron Ehrlich et al. Transl Androl Urol. 2015 Jun.

Abstract

Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented.

Keywords: Neoplasms germ cell tumor; chemotherapy; chemotherapy adjuvant; incidence; lymph node excision; neoplasm staging; orchiectomy; patient selection; treatment outcome.

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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