HSV Encephalitis with Normal CSF - A Case Report with Review of Literature
- PMID: 26816936
- PMCID: PMC4717694
- DOI: 10.7860/JCDR/2015/16999.6966
HSV Encephalitis with Normal CSF - A Case Report with Review of Literature
Abstract
Herpes simplex virus encephalitis (HSVE) is one of the most potentially fatal infectious disease that should be detected as early as possible. The combination of clinical history and examination, brain computed tomography or magnetic resonance imaging (MRI) and lumbar puncture have been used to establish a diagnosis. The authors present a case of HSVE with normal CSF analysis, but typical MRI findings consistent with HSE and CSF PCR positive for Herpes simplex virus1 DNA, who responded to Acyclovir therapy with complete recovery.
Keywords: Acyclovir; Cerebrospinal fluid; Herpes simplex virus; Polymerase chain reaction.
Figures
Similar articles
-
Herpes simplex viral encephalitis with acute memory impairment and low cellular cerebrospinal fluid: A case report with systematic review literature.IDCases. 2024 May 18;36:e01981. doi: 10.1016/j.idcr.2024.e01981. eCollection 2024. IDCases. 2024. PMID: 38831962 Free PMC article.
-
Comparing molecular quantification of herpes simplex virus (HSV) in cerebrospinal fluid (CSF) with quantitative structural and functional disease severity in patients with HSV encephalitis (HSVE): Implications for improved therapeutic approaches.J Clin Virol. 2018 Oct;107:29-37. doi: 10.1016/j.jcv.2018.08.005. Epub 2018 Aug 18. J Clin Virol. 2018. PMID: 30170224
-
[Early diagnosis of herpes simplex virus encephalitis by single photon emission computed tomography (SPECT) in patients with normal MRI].Rinsho Shinkeigaku. 1996 Mar;36(3):475-80. Rinsho Shinkeigaku. 1996. PMID: 8741353 Japanese.
-
Herpes simplex virus infections of the central nervous system: encephalitis and meningitis, including Mollaret's.Herpes. 2004 Jun;11 Suppl 2:57A-64A. Herpes. 2004. PMID: 15319091 Review.
-
Atypical brainstem encephalitis caused by herpes simplex virus 2.Arch Neurol. 2002 Mar;59(3):460-3. doi: 10.1001/archneur.59.3.460. Arch Neurol. 2002. PMID: 11890853 Review.
Cited by
-
Atypical Presentation of Varicella-Zoster Virus Encephalitis: A Case Report.Cureus. 2024 Sep 8;16(9):e68926. doi: 10.7759/cureus.68926. eCollection 2024 Sep. Cureus. 2024. PMID: 39381450 Free PMC article.
-
HSV-Encephalitis Reactivation after Cervical Spine Surgery.Case Rep Surg. 2019 Apr 10;2019:2065716. doi: 10.1155/2019/2065716. eCollection 2019. Case Rep Surg. 2019. PMID: 31093411 Free PMC article.
-
Screening Cerebrospinal Fluid Prior to Herpes Simplex Virus PCR Testing Might Miss Cases of Herpes Simplex Encephalitis.J Clin Microbiol. 2017 Oct;55(10):3142-3143. doi: 10.1128/JCM.01129-17. J Clin Microbiol. 2017. PMID: 28947509 Free PMC article. No abstract available.
-
Evaluation of Clinical and Paraclinical Findings for the Differential Diagnosis of Autoimmune and Infectious Encephalitis.Front Neurol. 2018 Jun 8;9:434. doi: 10.3389/fneur.2018.00434. eCollection 2018. Front Neurol. 2018. PMID: 29951031 Free PMC article.
-
Prospective, Cross-Sectional Study Finds No Common Viruses in Cerebrospinal Fluid of Children with Pseudotumor Cerebri.Brain Sci. 2023 Feb 19;13(2):361. doi: 10.3390/brainsci13020361. Brain Sci. 2023. PMID: 36831904 Free PMC article.
References
-
- Skelly MJ, Burger AA, Adekola O. Herpes simplex virus-1 encephalitis: a review of current disease management with three case reports. Antivir Chem Chemother. 2012;23(1):13–18. - PubMed
-
- Panagariya A, Jain RS, Gupta S, Garg A, Sureka RK, Mathur V. Herpes simplex encephalitis in North West India. Neurol India. 2001;49(4):360–65. - PubMed
-
- Tyler KL. Herpes simplex virus infections of the central nervous system: Encephalitis and meningitis, including Mollaret’s. Herpes. 2004;11(Suppl 2):57A–64A. - PubMed
Publication types
LinkOut - more resources
Full Text Sources