Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Dec;9(12):OD06-7.
doi: 10.7860/JCDR/2015/16999.6966. Epub 2015 Dec 1.

HSV Encephalitis with Normal CSF - A Case Report with Review of Literature

Gautam Rawal  1 , Sankalp Yadav  2 , Umar Rasool Wani  3 , Alok Kumar Ambastha  4
Affiliations
Case Reports

HSV Encephalitis with Normal CSF - A Case Report with Review of Literature

Gautam Rawal et al. J Clin Diagn Res. 2015 Dec.

Abstract

Herpes simplex virus encephalitis (HSVE) is one of the most potentially fatal infectious disease that should be detected as early as possible. The combination of clinical history and examination, brain computed tomography or magnetic resonance imaging (MRI) and lumbar puncture have been used to establish a diagnosis. The authors present a case of HSVE with normal CSF analysis, but typical MRI findings consistent with HSE and CSF PCR positive for Herpes simplex virus1 DNA, who responded to Acyclovir therapy with complete recovery.

Keywords: Acyclovir; Cerebrospinal fluid; Herpes simplex virus; Polymerase chain reaction.

PubMed Disclaimer

Figures

[Table/Fig-1]:
[Table/Fig-1]:
T2W CE MRI brain
[Table/Fig-2]:
[Table/Fig-2]:
Flair image of CE MRI brain-showing bilateral temporal hyper intensities (Right > Left) involving the medial temporal lobes.
See this image and copyright information in PMC

References

    1. Kennedy PG, Chaudhuri A. Herpes simplex encephalitis. J Neurol Neurosurg Psychiatry. 2002;73(3):237–38. - PMC - PubMed
    1. Skelly MJ, Burger AA, Adekola O. Herpes simplex virus-1 encephalitis: a review of current disease management with three case reports. Antivir Chem Chemother. 2012;23(1):13–18. - PubMed
    1. Domingues RB, Lakeman FD, Mayo MS, Whitley RJ. Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis. J Clin Microbiol. 1998;36:2229–34. - PMC - PubMed
    1. Panagariya A, Jain RS, Gupta S, Garg A, Sureka RK, Mathur V. Herpes simplex encephalitis in North West India. Neurol India. 2001;49(4):360–65. - PubMed
    1. Tyler KL. Herpes simplex virus infections of the central nervous system: Encephalitis and meningitis, including Mollaret’s. Herpes. 2004;11(Suppl 2):57A–64A. - PubMed

Publication types

LinkOut - more resources