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Clinical Trial
. 1989 Oct;82(10):598-9.
doi: 10.1177/014107688908201011.

Placental angiogenic and growth factors in the treatment of chronic varicose ulcers: preliminary communication

H Burgos  1 , A Herd, J P Bennett
Affiliations
Clinical Trial

Placental angiogenic and growth factors in the treatment of chronic varicose ulcers: preliminary communication

H Burgos et al. J R Soc Med. 1989 Oct.

Abstract

A short-term clinical study on the effect of purified angiogenic and growth factors from human term placenta in the treatment of chronic varicose ulcers was carried out in 18 patients. Patients were randomly allocated to receive a maximum of two dressings containing or not containing these factors. The amount of granulation and epithelial tissue was clinically estimated 48 hours after each application. Patients treated with placental angiogenic and growth factors showed increased granulation and epithelial tissue. These results indicate that placental factors may be used for acceleration of wound healing.

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