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Observational Study
. 2016 Jan;95(3):e2314.
doi: 10.1097/MD.0000000000002314.

Influence of Educational Level, Stage, and Histological Type on Survival of Oral Cancer in a Brazilian Population: A Retrospective Study of 10 Years Observation

Thinali Sousa Dantas  1 , Paulo Goberlânio de Barros Silva, Eric Fernandes Sousa, Maria do Pss da Cunha, Andréa Silvia Walter de Aguiar, Fábio Wildson Gurgel Costa, Mário Rogério Lima Mota, Ana Paula Negreiros Nunes Alves, Fabrício Bitu Sousa
Affiliations
Observational Study

Influence of Educational Level, Stage, and Histological Type on Survival of Oral Cancer in a Brazilian Population: A Retrospective Study of 10 Years Observation

Thinali Sousa Dantas et al. Medicine (Baltimore). 2016 Jan.

Abstract

The mortality rate associated with oral cancer is estimated at approximately 12,300 deaths per year, and the survival rate is only 40% to 50% for diagnosed patients and is closely related to the duration of time between disease perception and its diagnosis and treatment. Socioeconomic risk factors are determinants of the incidence and mortality related to oral cancer. We conducted a retrospective, cross-sectional study of 573 records of patients with oral cancer at Haroldo Juaçaba Hospital - Cancer Institute of Ceará from 2000 to 2009 to evaluate the influence of socioeconomic factors on survival and epidemiological behavior of this neoplasia in a Brazilian population. In this study, patients with oral cancer were males greater than 60 years of age, presented squamous cell carcinoma in the floor of mouth and were characterized by low education levels. A total of 573 lesions were found in oral cavities. Cox proportional hazards regression model showed that the histological type, tumor stage, and low degree of education significantly influenced survival. A lower patient survival rate was correlated with a more advanced stage of disease and a worse prognosis. Squamous cell carcinoma is associated with a higher mortality when compared with other histological types of malign neoplasia.

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Conflict of interest statement

The authors have no conflicts of interests to disclose.

Figures

FIGURE 1
FIGURE 1
Ten-year survival of patients diagnosed with oral cancer in Haroldo Juaçaba Hospital (2000–2009) (long-rank Mantel–Cox).
See this image and copyright information in PMC

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