Review

. 2016 Feb;36(2):e1-8.

doi: 10.1161/ATVBAHA.115.306350.

Systems Biology and Noninvasive Imaging of Atherosclerosis

Claudia Calcagno¹, Willem J M Mulder², Matthias Nahrendorf², Zahi A Fayad²

Affiliations

¹ From the Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (C.C., W.J.M.M., Z.A.F.); Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands (W.J.M.M.); and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (M.N.). claudia.calcagno@mssm.edu.
² From the Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (C.C., W.J.M.M., Z.A.F.); Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands (W.J.M.M.); and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (M.N.).

PMID: 26819466
PMCID: PMC4861402
DOI: 10.1161/ATVBAHA.115.306350

Review

Systems Biology and Noninvasive Imaging of Atherosclerosis

Claudia Calcagno et al. Arterioscler Thromb Vasc Biol. 2016 Feb.

. 2016 Feb;36(2):e1-8.

doi: 10.1161/ATVBAHA.115.306350.

Authors

Claudia Calcagno¹, Willem J M Mulder², Matthias Nahrendorf², Zahi A Fayad²

Affiliations

¹ From the Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (C.C., W.J.M.M., Z.A.F.); Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands (W.J.M.M.); and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (M.N.). claudia.calcagno@mssm.edu.
² From the Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY (C.C., W.J.M.M., Z.A.F.); Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands (W.J.M.M.); and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (M.N.).

PMID: 26819466
PMCID: PMC4861402
DOI: 10.1161/ATVBAHA.115.306350

No abstract available

Keywords: atherosclerosis; cardiovascular diseases; inflammation; lipids; risk factors.

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Figures

**Figure 1**
Schematic representation of the integration between data from high-throughput ‘-omics’ and imaging phenotypes in a systems biology approach, focused on building biological networks from genes and molecules, up to tissues and organs to study disease mechanisms.

See this image and copyright information in PMC

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Zupančič E, Fayad ZA, Mulder WJM. Zupančič E, et al. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):e167-e171. doi: 10.1161/ATVBAHA.117.309227. Arterioscler Thromb Vasc Biol. 2017. PMID: 29070539 Free PMC article. Review. No abstract available.

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References

1. Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA. Imaging systemic inflammatory networks in ischemic heart disease. Journal of the American College of Cardiology. 2015;65:1583–1591. - PMC - PubMed
1. Https://www.Framinghamheartstudy.Org.
1. Mayr M, Zampetaki A, Willeit P, Willeit J, Kiechl S. Micrornas within the continuum of postgenomics biomarker discovery. Arteriosclerosis, thrombosis, and vascular biology. 2013;33:206–214. - PubMed
1. Virmani R, Ladich ER, Burke AP, Kolodgie FD. Histopathology of carotid atherosclerotic disease. Neurosurgery. 2006;59:S219–227. discussion S213-213. - PubMed
1. Virmani R, Burke AP, Farb A, Kolodgie FD. Pathology of the vulnerable plaque. J Am Coll Cardiol. 2006;47:C13–18. - PubMed

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Systems Biology and Noninvasive Imaging of Atherosclerosis

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