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. 2015 Dec;15(4):256-61.
doi: 10.5230/jgc.2015.15.4.256. Epub 2015 Dec 31.

Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis

Hossein Fallahzadeh  1 , Ali Jalali  2 , Mahdieh Momayyezi  1 , Soheila Bazm  3
Affiliations

Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis

Hossein Fallahzadeh et al. J Gastric Cancer. 2015 Dec.

Abstract

Purpose: Gastric cancer is the third leading cause of cancer-related mortality, with the incidence and mortality being higher in men than in women. Various studies have shown that eating carrots may play a major role in the prevention of gastric cancer. We conducted a meta-analysis to determine the relationship between carrot consumption and gastric cancer.

Materials and methods: We searched multiple databases including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx. The following search terms were used: stomach or gastric, neoplasm or cancer, carcinoma or tumor, and carrot. Statistical analyses were performed using Comprehensive Meta Analysis/2.0 software.

Results: We retrieved 81 articles by searching the databases. After considering the inclusion and exclusion criteria, 5 articles were included in this study. The odds ratio (OR) obtained by fixed effects model showed that a 26% reduction in the risk of gastric cancer has been associated with the consumption of carrots) OR=0.74; 95% confidence interval=0.68~0.81; P<0.0001). According to funnel graph, the results showed that the possibility of a publication bias does not exist in this study.

Conclusions: The findings of this study showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

Keywords: Carcinoma; Daucus carota; Neoplasm; Stomach.

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Conflict of interest statement

Conflicts of Interest: No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1. Flow chart of study selection.
Fig. 2
Fig. 2. Forest plot of relationship between the consumption of carrots and gastric cancer. Blank = the absence of subgroups in the study; FHGC- = No family history of gastric cancer; FHGC+ = family history of gastric cancer; CI = confidence interval.
Fig. 3
Fig. 3. Funnel plot of relationship between the consumption of carrots and gastric cancer.
See this image and copyright information in PMC

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