Cellular localization of heat shock gene expression in rabbit cerebellum by in situ hybridization with plastic-embedded tissue
- PMID: 2682331
- DOI: 10.1007/BF00964949
Cellular localization of heat shock gene expression in rabbit cerebellum by in situ hybridization with plastic-embedded tissue
Abstract
The major cell types in rabbit cerebellum which engage in the expression of a heat shock gene (hsp70) after hyperthermia were identified. This required in situ hybridization on thin sections derived from plastic-embedded tissue. All classes of cerebellar neurons which were examined (Purkinje, granule, and stellate cells) responded by induction of hsp70 mRNA within 1 hr after hyperthermia. Prominent induction of hsp70 mRNA was also observed in oligodendroglia in the deep white matter.
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