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Comment
. 2016 Jan 28;127(4):373-4.
doi: 10.1182/blood-2015-12-686592.

Mast cell differentiation: still open questions?

Michel Arock  1
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Free article
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Mast cell differentiation: still open questions?

Michel Arock. Blood. .
Free article

Abstract

In this issue of Blood, Dahlin et al report on a minor circulating human mast cell (MC) progenitor cell population (lineage-negative [Lin−]/CD34hi/CD117int/hi/high-affinity immunoglobulin E receptor-positive [FcεRI+]), with an immature MC-like appearance, which is present in the peripheral blood (PB) of healthy individuals and of asthma subjects well controlled by treatment or with reduced lung function.

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