The Importance of Timing
- PMID: 26824651
- DOI: 10.1016/j.cell.2016.01.010
The Importance of Timing
Abstract
Building a nervous system requires a precise sequence of genetic transitions, mediated in part by the temporal and spatial regulation of transcription factors. Quan et al. add to our understanding of this regulation by describing an evolutionarily conserved post-translational mechanism that rapidly extinguishes proneural protein activity in neural precursors.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis.Cell. 2016 Jan 28;164(3):460-75. doi: 10.1016/j.cell.2015.12.048. Cell. 2016. PMID: 26824657
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