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Comment
. 2016 Jan 28;164(3):347-8.
doi: 10.1016/j.cell.2016.01.010.

The Importance of Timing

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The Importance of Timing

Richard S Mann et al. Cell. .
Free article

Abstract

Building a nervous system requires a precise sequence of genetic transitions, mediated in part by the temporal and spatial regulation of transcription factors. Quan et al. add to our understanding of this regulation by describing an evolutionarily conserved post-translational mechanism that rapidly extinguishes proneural protein activity in neural precursors.

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