Cutaneous Metastasis of Rectal Cancer: A Case Report and Literature Review

Abstract

Cutaneous metastasis of rectal cancer is rare. It typically indicates widespread disease and poor prognosis. We report an exceedingly rare case of rectal cancer with metastasis to the skin and review the literature on cutaneous metastasis of rectal cancer. A 47-year-old man presented with stage IV unresectable adenocarcinoma of the rectum and received palliative chemoradiation for local pain control. About a year later he developed extensive skin lesions involving the genital area, bilateral groin, and perineum. Biopsy specimen showed mucinous adenocarcinoma compatible with rectal origin. Palliative treatment with radiation therapy was initiated. The patient responded well to treatment and is still alive more than a year after diagnosis of cutaneous metastasis. Surgeons should maintain strong suspicion of cutaneous metastases when patients with rectal cancer have new or evolving skin lesions.

Figure 1.

Computed tomography image of the rectal tumor and the left inguinal lymphadenopathy (86 mm × 49 mm).

Figure 2.

Computed tomography image of the aortocaval lymphadenopathy (87 mm × 48 mm).

Figure 3.

Perineal, bilateral groin, and genital skin metastases (86 mm × 69 mm).